Bailor

Shizuo Akira, M.D., Ph.D.

WPI Immunology Frontier Research Center, Osaka University,

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Distribution for a fee Guide Knockout mouse

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ŸTLR family Knockout mouse

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ƒeƒLƒXƒg ƒ{ƒbƒNƒX: Natural immunomechanism by TLR

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Background

Reference

MyD88

C57BL/6 , BALB/c

Adachi, O. et al., 1998. Immunity.

9: 143-150.

TLR1

C57BL/6

Takeuchi, O. et al., 2002. J Immunol. 169: 10-14.

TLR2

C57BL/6 , BALB/c

Takeuchi, O. et al., 1999. Immunity.

11: 443-451.

TLR4

C57BL/6 , BALB/c

Hoshino, K. et al., 1999. J@Immunol. 162: 3749-3752.

TLR6

C57BL/6

Takeuchi, O. et al., 2001. Int Immunol. 13: 933-940.

TLR7

C57BL/6 , BALB/c

Hemmi, H. et al., 2002. Nat Immunol.

3: 196-200.

TLR9

C57BL/6 , BALB/c

Hemmi, H. et al., 2000. Nature.

408: 740-745.

TLR2/4 double KO

C57BL/6

Immunity. 1999 Oct; 11(4) :443-51.

J Immunol. 1999 Apr 1;162(7) :3749-52

TLR7/9 double KO

C57BL/6

Nat Immunol. 2002 Feb;3(2) :196-200

Nature. 2000 Dec 7;408(6813) :740-5